|
Symbol Name ID |
Stk11
serine/threonine kinase 11 MGI:1341870 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Precocious puberty with Sertoli cell tumor |
Enlarged polycystic ovaries |
Ovarian cyst |
Ovarian carcinoma |
Cervix cancer |
Uterine neoplasm |
| Disease(s) Associated with STK11 | ||||||
| pancreatic cancer | ||||||
| Peutz-Jeghers syndrome |
| Mouse Phenotypes | reproductive system phenotype |
decreased male germ cell number |
increased Sertoli cell proliferation |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
abnormal seminiferous tubule epithelium morphology |
abnormal Sertoli cell morphology |
decreased testis weight |
small testis |
increased endometrial carcinoma incidence |
abnormal myometrium morphology |
abnormal uterus size |
increased uterus weight |
abnormal spermatogenesis |
male infertility |
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| Availability | Mouse Genotype | |||||||||||||||
| Stk11tm1.1Arte/Stk11tm1.1Arte | * | |||||||||||||||
| Stk11tm1Keis/Stk11tm1Keis | ||||||||||||||||
| Stk11tm1.2Rdp/Stk11+ | ||||||||||||||||
| Stk11tm1Tpm/Stk11+ | ||||||||||||||||
| Stk11tm1.1Rdp/Stk11tm1.1Rdp (conditional) | ||||||||||||||||
| Stk11tm1.1Rdp/Stk11tm1.1Rdp Tg(Sprr2f-cre)1Dcas/0 (conditional) |
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| Stk11tm1Keis/Stk11tm1Keis Tg(Ckmm-cre)5Khn/0 (conditional) |
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| Amhr2tm3(cre)Bhr/Amhr2+ Stk11tm1Rdp/Stk11tm1Rdp (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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